Enzymology, Receptors and Signal Transduction

Enzymology

Dicarbonyl synthases

• Amadoriase
• Methylglyoxal synthase
• Others

Enzymatic defence against glycation

• Overview
• Fructosamine 3-phosphokinase
• The glyoxalase system
• Aldehyde reductases and dehydrogenases

AGE Receptors

• Overviews
• Oligosaccharyltransferase-48 (OST-48 or AGE-R1)
• 80K-H (or AGE-R2)
• Galectin-3 (or AGE-R3)
• Receptor for advanced glycation endproducts
• Scavenger receptors
• Other AGE-binding proteins

Cell signalling

• AGE receptor signalling
• Glycation of transcription factors

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